NFL Off an upset loss: San Francisco 49ers: ATS Record Since 1999
Lost last week as a favorite. 72 team-games since 1999.
Against the spread: 38-30-4 (55.9%)
Straight up: 41-31 (56.9%)
Over/under: 31-39-2 (44.3% overs)
Average cover margin: 1.13 points
Is it real?
A bettor with no edge makes this much profit about 1 in 4 times, so it is consistent with luck. 1999-2012: 16-10 (61.5%); 2013-2025: 22-20 (52.4%). Break-even at -110 is 52.4%.
This week’s games that fit
- 2026-11-08: SF vs LV
By season
| Season | ATS | Cover % |
|---|---|---|
| 2025 | 1-0 | 100.0% |
| 2024 | 3-4 | 42.9% |
| 2023 | 2-3 | 40.0% |
| 2022 | 2-1 | 66.7% |
| 2021 | 4-2 | 66.7% |
| 2020 | 3-3 | 50.0% |
| 2019 | 0-1-1 | 0.0% |
| 2018 | 2-1 | 66.7% |
| 2017 | 1-0 | 100.0% |
| 2016 | 0-2 | 0.0% |
| 2014 | 2-3-1 | 40.0% |
| 2013 | 2-0 | 100.0% |
| 2012 | 3-1 | 75.0% |
| 2011 | 1-0 | 100.0% |
| 2010 | 4-1 | 80.0% |
| 2009 | 2-0-1 | 100.0% |
| 2008 | 1-0 | 100.0% |
| 2006 | 2-0 | 100.0% |
| 2004 | 0-1 | 0.0% |
| 2003 | 1-1 | 50.0% |
| 2002 | 0-3-1 | 0.0% |
| 2001 | 1-0 | 100.0% |
| 2000 | 1-0 | 100.0% |
| 1999 | 0-3 | 0.0% |
Questions
What is the ATS record of NFL off an upset loss for the San Francisco 49ers?
38-30-4 against the spread (55.9%) in 72 team-games since 1999, 41-31 straight up and 31-39-2 on the over/under.
Is this trend likely to be luck?
A bettor with no edge makes this much profit about 1 in 4 times, so it is consistent with luck.
Did it hold up?
1999-2012: 16-10 (61.5%); 2013-2025: 22-20 (52.4%).