Iowa State Cyclones predictions and picks

Mako Bets writes a full preview of every Iowa State Cyclones game: the matchup, the players who decide it, injuries and the line.

Earlier previews

• Iowa State Cyclones vs Oklahoma State Cowboys prediction · Sat, Oct 31, 2026 · Oklahoma State -9.5, total 58
  Mestemaker's 300-yard streak heads to a short-handed Iowa State front
• Iowa State Cyclones at Arizona Wildcats prediction · Sat, Oct 24, 2026 · Arizona -11, total 51.5
  Noah Fifita and Arizona chase bowl eligibility against a fading Cyclones defense

All College Football predictions