Louisville Cardinals predictions and picks

Mako Bets writes a full preview of every Louisville Cardinals game: the matchup, the players who decide it, injuries and the line.

Earlier previews

• Louisville Cardinals vs Stanford Cardinal prediction · Sat, Oct 31, 2026 · Louisville -22.5, total 60.5
  Louisville's big-play offense faces a Stanford defense that ranks last
• Louisville Cardinals at Syracuse Orange prediction · Sat, Oct 17, 2026 · Louisville -14.5, total 55.5
  Syracuse hunts for a quarterback as Louisville's backs keep breaking loose

All College Football predictions