| 2026-07-11 | Nikita Krylov | 12-9 | Grappler | W | KO/TKO R3 1:01 | UFC 329: McGregor vs. Holloway 2 |
| 2025-07-26 | Reinier de Ridder | 3-0 | Grappler | L | Decision - Split R5 5:00 | UFC Fight Night: Whittaker vs. De Ridder |
| 2024-10-26 | Khamzat Chimaev | 7-0 | Grappler | L | Submission R1 3:34 | UFC 308: Topuria vs. Holloway |
| 2024-06-22 | Ikram Aliskerov | 2-0 | — | W | KO/TKO R1 1:49 | UFC Fight Night: Whittaker vs. Aliskerov |
| 2024-02-17 | Paulo Costa | 6-2 | Striker | W | Decision - Unanimous R3 5:00 | UFC 298: Volkanovski vs. Topuria |
| 2023-07-08 | Dricus Du Plessis | 5-0 | Grappler | L | KO/TKO R2 2:23 | UFC 290: Volkanovski vs. Rodriguez |
| 2022-09-03 | Marvin Vettori | 8-3-1 | Wrestler | W | Decision - Unanimous R3 5:00 | UFC Fight Night: Gane vs. Tuivasa |
| 2022-02-12 | Israel Adesanya | 10-1 | Striker | L | Decision - Unanimous R5 5:00 (title) | UFC 271: Adesanya vs. Whittaker 2 |
| 2021-04-17 | Kelvin Gastelum | 11-6 (1 NC) | Balanced | W | Decision - Unanimous R5 5:00 | UFC Fight Night: Whittaker vs. Gastelum |
| 2020-10-24 | Jared Cannonier | 6-4 | Striker | W | Decision - Unanimous R3 5:00 | UFC 254: Khabib vs. Gaethje |
| 2020-07-25 | Darren Till | 6-2-1 | Balanced | W | Decision - Unanimous R5 5:00 | UFC Fight Night: Whittaker vs. Till |
| 2019-10-05 | Israel Adesanya | 6-0 | Striker | L | KO/TKO R2 3:33 (title) | UFC 243: Whittaker vs. Adesanya |
| 2018-06-09 | Yoel Romero | 9-1 | Wrestler | W | Decision - Split R5 5:00 | UFC 225: Whittaker vs. Romero 2 |
| 2017-07-08 | Yoel Romero | 8-0 | Wrestler | W | Decision - Unanimous R5 5:00 (title) | UFC 213: Romero vs. Whittaker |
| 2017-04-15 | Jacare Souza | 7-1 | Grappler | W | KO/TKO R2 3:28 | UFC on FOX: Johnson vs. Reis |
| 2016-11-26 | Derek Brunson | 7-1 | Wrestler | W | KO/TKO R1 4:07 | UFC Fight Night: Whittaker vs. Brunson |
| 2016-04-23 | Rafael Natal | 9-4-1 | Wrestler | W | Decision - Unanimous R3 5:00 | UFC 197: Jones vs Saint Preux |
| 2015-11-14 | Uriah Hall | 5-3 | Balanced | W | Decision - Unanimous R3 5:00 | UFC 193: Rousey vs Holm |
| 2015-05-09 | Brad Tavares | 8-3 | Balanced | W | KO/TKO R1 0:44 | UFC Fight Night: Miocic vs Hunt |
| 2014-11-07 | Clint Hester | 4-0 | Striker | W | KO/TKO R2 2:43 | UFC Fight Night: Rockhold vs Bisping |
| 2014-06-28 | Mike Rhodes | 0-1 | Grappler | W | Decision - Unanimous R3 5:00 | UFC Fight Night: Te Huna vs Marquardt |
| 2014-02-22 | Stephen Thompson | 3-1 | Striker | L | KO/TKO R1 3:43 | UFC 170: Rousey vs McMann |
| 2013-08-28 | Court McGee | 4-2 | Wrestler | L | Decision - Split R3 5:00 | UFC Fight Night: Condit vs Kampmann 2 |
| 2013-05-25 | Colton Smith | 1-0 | Grappler | W | KO/TKO R3 0:41 | UFC 160: Velasquez vs Silva 2 |
| 2012-12-14 | Brad Scott | UFC debut | — | W | Decision - Unanimous R3 5:00 (title) | UFC on FX: Sotiropoulos vs Pearson |