| 2024-11-16 | Stipe Miocic | 14-4 | Striker | W | KO/TKO R3 4:29 (title) | UFC 309: Jones vs. Miocic |
| 2023-03-04 | Ciryl Gane | 8-1 | Striker | W | Submission R1 2:04 (title) | UFC 285: Jones vs. Gane |
| 2020-02-08 | Dominick Reyes | 6-0 | Striker | W | Decision - Unanimous R5 5:00 (title) | UFC 247: Jones vs. Reyes |
| 2019-07-06 | Thiago Santos | 13-5 | Striker | W | Decision - Split R5 5:00 (title) | UFC 239: Jones vs. Santos |
| 2019-03-02 | Anthony Smith | 7-3 | Balanced | W | Decision - Unanimous R5 5:00 (title) | UFC 235: Jones vs. Smith |
| 2018-12-29 | Alexander Gustafsson | 10-4 | Striker | W | KO/TKO R3 2:02 (title) | UFC 232: Jones vs. Gustafsson 2 |
| 2017-07-29 | Daniel Cormier | 8-1 | Striker | NC | Overturned R3 3:01 (title) | UFC 214: Cormier vs. Jones 2 |
| 2016-04-23 | Ovince Saint Preux | 7-2 | Balanced | W | Decision - Unanimous R5 5:00 (title) | UFC 197: Jones vs Saint Preux |
| 2015-01-03 | Daniel Cormier | 4-0 | Striker | W | Decision - Unanimous R5 5:00 (title) | UFC 182: Jones vs Cormier |
| 2014-04-26 | Glover Teixeira | 5-0 | Grappler | W | Decision - Unanimous R5 5:00 (title) | UFC 172: Jones vs Teixeira |
| 2013-09-21 | Alexander Gustafsson | 7-1 | Grappler | W | Decision - Unanimous R5 5:00 (title) | UFC 165: Jones vs Gustafsson |
| 2013-04-27 | Chael Sonnen | 6-5 | Wrestler | W | KO/TKO R1 4:33 (title) | UFC 159: Jones vs Sonnen |
| 2012-09-22 | Vitor Belfort | 10-5 | Submission grappler | W | Submission R4 0:54 (title) | UFC 152: Jones vs Belfort |
| 2012-04-21 | Rashad Evans | 12-1-1 | Wrestler | W | Decision - Unanimous R5 5:00 (title) | UFC 145: Jones vs Evans |
| 2011-12-10 | Lyoto Machida | 9-2 | Balanced | W | Submission R2 4:26 (title) | UFC 140: Jones vs Machida |
| 2011-09-24 | Quinton Jackson | 7-2 | Balanced | W | Submission R4 1:14 (title) | UFC 135: Jones vs Rampage |
| 2011-03-19 | Mauricio Rua | 3-2 | Balanced | W | KO/TKO R3 2:37 (title) | UFC 128: Shogun vs Jones |
| 2011-02-05 | Ryan Bader | 5-0 | Wrestler | W | Submission R2 4:20 | UFC 126: Silva vs Belfort |
| 2010-08-01 | Vladimir Matyushenko | 5-2 | Wrestler | W | KO/TKO R1 1:52 | UFC Live: Jones vs Matyushenko |
| 2010-03-21 | Brandon Vera | 7-4 | Balanced | W | KO/TKO R1 3:19 | UFC Live: Vera vs Jones |
| 2009-12-05 | Matt Hamill | 6-2 | Wrestler | L | DQ R1 4:14 | The Ultimate Fighter: Heavyweights Finale |
| 2009-07-11 | Jake O'Brien | 4-2 | Wrestler | W | Submission R2 2:43 | UFC 100 |
| 2009-01-31 | Stephan Bonnar | 5-3 | Submission grappler | W | Decision - Unanimous R3 5:00 | UFC 94: St-Pierre vs Penn 2 |
| 2008-08-09 | Andre Gusmao | UFC debut | — | W | Decision - Unanimous R3 5:00 | UFC 87: Seek And Destroy |